Research and Development


PRESS RELEASE: Scottsdale, Arizona, - October 15, 2013 - Brain State Technologies®, developer of HIRREM™, a patented process to facilitate relaxation and auto-calibration of neural oscillations, is pleased to announce that two separate abstracts related to their signature technology have been accepted for poster presentation at the American Neurological Association Annual Meeting in New Orleans from October 13-15, 2013. The American Neurological Association is a professional society of academic neurologists and neuroscientists, and the posters are two of four that have been accepted for presentation at their meeting in the category of “Neurotechnology.” The posters describe studies conducted by Professor Charles Tegeler, M.D., at Wake Forest School of Medicine, who is supported by a research grant from The Susanne Marcus Collins Foundation, Inc.

The first poster, titled "Neural-oscillatory Intervention for Auto-calibration Improves EEG Symmetry and Heart Rate Variability," looks at the impact of HIRREM on Heart Rate Variability (HRV). Lower HRV may indicate reduced vagal tone, a trait associated with a large variety of neurological and psychophysiological conditions including post-traumatic stress, insomnia, traumatic brain injury, anxiety, and hot flashes. Researchers observed that improvement in EEG asymmetry as affected through application of HIRREM was accompanied by improvement in HRV. The findings “suggest a potential role of HIRREM for disorders associated with…autonomic dysregulation.”

The second poster is titled "High-resolution, Relational, Resonance-based Electroencephalic Mirroring (HIRREM) Reduces Symptoms and EEG Asymmetry in an Individual with PTSD." Building on previous studies linking PTSD to hemispheric imbalance in the brain, this abstract describes the reduction of EEG asymmetry and PTSD symptoms in an individual after undergoing the HIRREM process.

Conceived by Lee Gerdes and developed over the past decade by Brain State Technologies, the company he founded, HIRREM is more commonly known as Brainwave Optimization®. The patented process involves translating an individual’s brain wave activity as read by EEG sensors into audible tones of changing pitch and timing, and playing these spontaneously generated soundscapes back to the individual in real-time. Thus the technology creates a loop between the brain and its computer-processed auditory reflection. The process has been noted for its tendency to facilitate relaxation and self-adjustment of brain wave activity toward greater symmetry and optimized proportionation.

Dr. Sung Lee, Director of Research at Brain State Technologies, and members of the Wake Forest team that conducted the research will personally attend the Annual Meeting and will be available throughout the event for questions regarding the research and HIRREM. 

MEDIA NOTE: If you would like more information about Brain State Technologies® or Brainwave Optimization®, please contact Laura Dueker at 480.588.6840 or send an email to pr(at)brainstatetech(dot)com.

About Brain State Technologies ( Brain State Technologies® is the world’s leading provider of brainwave balancing technology, Brainwave Optimization®. Founded in 2001 and developed by Lee Gerdes, the modality combines the latest advances in neuroscience, neuroplasticity, computer technology, mathematics, and physics. Brainwave Optimization offers a non-invasive way for people of all ages to overcome cognitive, emotional, and physical challenges, and enhance overall performance and wellbeing. With over 50,000 clients and more than 200 affiliated centers in 20 countries, the company is growing by licensing Brainwave Optimization to providers worldwide.

Brain State Technologies®, Brainwave Optimization®, Brainwave Optimization with RTB™, Brain State®, HIRREM™, Intellifier®, Intellipoint®, Intellectrodes™, Intellisensors™, and Braintellect®, are all registered trademarks of Brain State Technologies, LLC. Unauthorized usage is in violation of various countries trademark laws. Brainwave Optimization with RTB® is not intended to treat, cure, heal, or diagnose any disease, mental illness or symptom. Brainwave Optimization with RTB® is intended to facilitate relaxation and auto-calibration of neural oscillations. Individual results may vary.


USA Today - September 2012

USA Today Click to read the article

Advancements in Sleep Technology: Dispatches from a New Yorker

I’m just your average New Yorker—if ever there were such a thing. No… I don’t spend each weekend strolling the High Line or taking trips to Governor’s Island.  But I do know exactly what time the Q train shows up at 14th Street during rush hour, and I can pretty much tell you where to get the best bagel, slice, or doughnut in the city (Kossar’s, L&B, Dough, respectively). And much like other New Yorkers, I can’t seem to sleep for more than a few hours at a time. And I miss sleep. So I dug up some newfound treasures that may help my quest to get in 8-hours.

Brainwave Optimization

Brainwave Optimization sounds a bit intimidating, but it’s really not. When we experience traumas, whether emotional or physical, our brain functions can become imbalanced. Dr. Sung Lee, Diplomate of the American Board of Internal Medicine and Research Coordinator at Brain State Technologies® explains, “When our brain is out of balance, this tends to manifest in ailments or disorders, such as stress, anxiousness and sleeplessness.” So how do we get things back in balance? “The Brainwave Assessment first evaluates any imbalances that are currently taking place,” explains Lee, “and it does so by placing small non-invasive sensors on the temples to record data. The data is then translated into sound, which is played back to the brain. Through sound, the brain is able to recognize the imbalances and recalibrate itself to find balance.” As Dr. Charles Tegeler, Neurologist at Wake Forest Baptist Health explains “When we look in the mirror, we may notice that our hair is off-kilter, and we’re able to fix it. In essence, this is what takes place when the brain listens to its own sound waves—it has that mirror-like quality to recognize the imbalance between brain lobes and fix it.” The result? In many cases, better sleep, less fatigue and stress, and a myriad of other benefits.

Sleep Monitoring Systems

My worst enemy tends to rest exactly next to me while I sleep. And, no, this is not a cheap shot at my wife. It’s my alarm clock. But these days, I’ve found a better solution than that blinding blue incandescent light. There are a few products on the market, like the Zeo Mobile Sleep Manager or The Lark Silent Alarm Clock, that connect to your body through your iPhone or Android. These products can not only analyze when you wake up throughout the night, they gently stir you awake you up when you’re in a state of shallow sleep in the mornings, which, according to the manufacturers, makes you feel more refreshed throughout the day.

Blue Light Technology

Traditional science and popular belief may suggest that staring at a light would probably not help anyone fall asleep, but sleep aid manufacturers and the millions of Americans suffering from sleep loss have found just the contrary in a little blue light. Two products are on the market:  the first product is called the Nightwave—an electronic sleep mask that shines blue light while blocking out any other light. The second is called the GloLight, which projects blue light upon the ceiling. Though these products are not for everyone, many have found them to be extremely helpful in creating a heavy-eyelid sensation that can effectively bore someone to sleep.

--Steve Fontana, Staff Writer


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Article and video originally posted at (April 3,2012) Click here to see article

"New treatment helping people with insomnia"

Reporter: Maureen McFadden

How did you sleep last night? If you have trouble getting enough Z's, you're not alone.

60 million Americans have insomnia and sometimes even sleeping pills don't help. Now a new experimental treatment could point the way to a good night's sleep.

45-year-old Howard Shelley couldn't sleep more than three hours a night.

Howard Shelley, Suffered from insomnia, describes the sleeping problems he had, "I wouldn't sleep that soundly, I would wake up."

Up to 50-percent of Americans like Howard report insomnia on a weekly basis. Now a new therapy could help.

Howard participated in the first clinical research study using brainwave optimization- essentially using your own brain waves to balance brain function, to improve sleep.

Charles Tegeler, MD, Neurologist, Wake Forest Baptist Medical Center, describes what the process is like, "It's kind of like pushing the reset button in that you get back to a balanced level to start with."

Doctor Charles Tegeler says insomnia can be caused by stress or trauma that throws off the brain's natural rhythms and balance.

Here's how it works is, sensors attach to the scalp and connect to a brain-mapping computer that detects brain waves. The brain waves are then broken down into frequencies and evaluated. Dominant frequencies are then assigned a musical tone and played back to the patient through ear phones.

Shelley describes what he sees the process, "It's kind of consonant, kind of dissonant, strangely ethereal."

As the brain listens to the sounds, changes can occur in the neural network.

Shelley explains how it helped him, "It works. After the third session, I got a great night's sleep. After that, little by little, the insomnia kind of went away. I'm sleeping great now."

All thanks to the sounds of his own brain.

Brain wave optimization is available as a biofeedback technique, but formal research studies are just emerging. The treatment has been shown to be safe and painless in early research trials for insomnia.

A clinical trial for brainwave optimization in migraines is also underway, with additional studies planned for people with concussions.

REPORT# 1871

BACKGROUND: Insomnia is a sleeping disorder that affects millions of individuals worldwide. Research has linked insomnia to high blood pressure, congestive heart failure, diabetes and other medical issues. Not only does insomnia cause sleepiness during the day, it has been linked to deeper problems such as high blood pressure, congestive heart failure, diabetes and other ailments. Insomnia can fluctuate throughout one's life and can be somewhat difficult to diagnose due to the variations of the disorder. The American Academy of Sleep Medicine has developed 11 variations of insomnia. (Source:,

DO YOU HAVE INSOMNIA? Insomnia is characterized by difficulty falling and/or staying asleep. Insomnia can be caused by many different factors including anxiety, medications, stress, caffeine, overeating before bedtime or a change in one's life. Many people are unaware that they are suffering from insomnia, but there are a few common symptoms: 
* Difficulty falling asleep
* Waking up often during the night and having trouble going back to sleep
* Waking up too early in the morning
* Feeling tired upon waking

TYPES OF INSOMNIA: There are two classifications of insomnia: primary insomnia and secondary insomnia.
* Primary insomnia occurs when a person is having sleep problems that are not directly related to any other health condition or problem.
* Secondary insomnia occurs when a person is having sleep problems because of something else, such as asthma, depression, arthritis, cancer or heartburn. (Source:

INSOMNIA TREATMENT: Brainwave optimization is a non-invasive treatment that helps the brain balance itself for optimal performance. The therapy is still considered experimental for the treatment of insomnia but there are treatment facilities offering the therapy for other disorders. Reports show that many patients meet the treatment expectations or exceed them. (Source:,,